All service and manufacturing businesses are resilient and strive for a more efficient and better end in today's world. Data mining is data-driven and necessitates significant data to analyze the pattern and train the model. Assume the data is incorrect and was not coll More
All service and manufacturing businesses are resilient and strive for a more efficient and better end in today's world. Data mining is data-driven and necessitates significant data to analyze the pattern and train the model. Assume the data is incorrect and was not collected from reliable sources, causing the analysis to be skewed. We introduce a procedure in which the dataset is split into test and training datasets with a specific ratio to overcome this challenge. Process mining will find the traces of actions to streamline the process and aid data mining in producing a more efficient result. The most responsible domain is the healthcare industry. In this study, we used the activity data from the hospital and applied process mining algorithms such as alpha miner and fuzzy miner. Process mining is used to check for conformity in the event log and do performance analysis, and a pattern of accuracy is exhibited. Finally, we used process mining techniques to show the deviation flow and fix the process flow. This study showed that there was a variation in the flow by employing alpha and fuzzy miners in the hospital.
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In human physiology, cholesterol plays an imperative part in membrane cells which regulates the function of G-protein-coupled receptors (GPCR) family. Cholesterol is an individual type of lipid structure and about 90 percent of cellular cholesterol is present at plasma More
In human physiology, cholesterol plays an imperative part in membrane cells which regulates the function of G-protein-coupled receptors (GPCR) family. Cholesterol is an individual type of lipid structure and about 90 percent of cellular cholesterol is present at plasma membrane region. Cholesterol Recognition/interaction Amino acid Consensus (CRAC) sequence, generally referred as the CRAC (L/V)-X1−5-(Y)-X1−5-(K/R) and the new cholesterol-binding domain is similar to the CRAC sequence, but exhibits the inverse orientation along the polypeptide chain i.e. CARC (K/R)-X1−5-(Y/F)-X1−5-(L/V). GPCR is treated as a biggest super family in human physiology and probably more than 900 protein genes included in this family. Among all membrane proteins GPCR is responsible for novel drug discovery in all pharmaceuticals industry. In earlier researches the researchers did not find the required number of valid motifs in terms of helices and motif types so they were lacking clinical relevance. The research gap here is that they were not able to predict the motifs effectively which are belonging to multiple motif types. To find out better motif sequences from human GPCR, we explored a hybrid computational model consisting of hybridization of Rough Set with Mean-Shift algorithm. In this paper we made comparison among our resulted output with other techniques such as fuzzy C-means (FCM), FCM with spectral clustering and we concluded that our proposed method targeted well on CRAC region in comparison to CARC region which have higher biological relevance in medicine industry and drug discovery.
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